Description

2-(3-Aminopropanoylamino)-3-(3H-Imidazol-4-Yl)Propanoic Acid is a high-purity, non-proteinogenic amino acid derivative featuring both an imidazole ring and a peptide-like amide linkage. This compound is valued for its role as a sophisticated building block in advanced organic synthesis and pharmaceutical research. It is primarily utilized by R&D chemists and manufacturers in the pharmaceutical, biochemical, and peptide synthesis sectors for developing novel active compounds and biochemical probes.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting enzyme inhibition or receptor modulation.
• Peptide Mimetic Research: Used to incorporate imidazole and amide functionalities into peptide backbones to study structure-activity relationships and enhance bioavailability.
• Biochemical Reagent: Serves as a specialized substrate or inhibitor in enzymatic studies and biochemical assays.
• Ligand Synthesis: Employed in the development of chelating agents or metal-organic frameworks (MOFs) due to its multiple coordination sites.
• Academic & Industrial R&D: A valuable tool for chemical biology research and the discovery of new bioactive molecules.

Basic Information

Item	Detail
Product Name	2-(3-Aminopropanoylamino)-3-(3H-Imidazol-4-Yl)Propanoic Acid
CAS No.	7683-28-5
Molecular Formula	C9H14N4O3
Molecular Weight	226.23 g/mol
Synonyms	Nα-(3-Aminopropionyl)histidine; Histidine, N-(3-aminopropanoyl)-; 3-[(3-Aminopropanoyl)amino]-3-(1H-imidazol-4-yl)propanoic acid; L-Histidine, N-(3-aminopropanoyl)-; NSC 113928; 2-[(3-Aminopropanoyl)amino]-3-(1H-imidazol-4-yl)propanoic acid; AHA-Histidine; 3-Aminopropionylhistidine
EINECS	Contact for details

Quality Control

Our production of 2-(3-Aminopropanoylamino)-3-(3H-Imidazol-4-Yl)Propanoic Acid adheres to stringent internal quality standards to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We support cGMP and ISO-aligned practices for research and development applications. Certificates of Analysis (COA) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.