Description

n-Acetyl-Dl-Norleucine is a chemically modified derivative of the amino acid norleucine, featuring an acetyl group on its α-amino nitrogen. This modification enhances its stability and makes it a valuable building block and intermediate in sophisticated organic synthesis. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and biotechnology sectors for applications such as peptide synthesis and biochemical research.

Application

• Pharmaceutical Intermediate: A key chiral building block in the synthesis of novel active pharmaceutical ingredients (APIs) and peptide-based drugs.
• Peptide Synthesis: Used as a protected amino acid derivative in solid-phase and solution-phase peptide synthesis to study structure-activity relationships.
• Biochemical Research: Serves as a substrate or inhibitor in enzymatic studies and metabolic pathway investigations.
• Reference Standard: Employed as a high-purity analytical standard in quality control laboratories for method development and validation.
• Chemical Biology: Utilized in the development of probes and tools for studying protein function and interactions.
• Academic & Industrial R&D: A fundamental reagent for exploring new synthetic methodologies and creating specialized chemical libraries.

Basic Information

Product Name	n-Acetyl-Dl-Norleucine
CAS No.	7682-16-8
Molecular Formula	C8H15NO3
Molecular Weight	173.21 g/mol
Synonyms	Ac-DL-Nle-OH; 2-Acetamidohexanoic Acid; DL-2-Acetamidocaproic Acid; N-Acetyl-DL-norleucine; N-Acetyl-DL-2-aminohexanoic Acid; N-Acetyl-DL-α-amino-n-caproic Acid; Norleucine, N-acetyl-, DL-; (±)-2-Acetamidohexanoic Acid
EINECS	231-672-8

Quality Control

Our n-Acetyl-Dl-Norleucine is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets exacting standards for research and synthesis. Certificates of Analysis (COA) with detailed specifications are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after use to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation	± 0.5° (c=1 in H2O)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.