Description

(2S,3S,4S,5R,6S)-6-[[(10R,13S)-10,13-Dimethyl-17-Oxo-1,2,7,8,9,11,12,14,15,16-Decahydrocyclopenta[A]Phenanthren-3-Yl]Oxy]-3,4,5-Trihydroxy-Oxane-2-Carboxylic Acid is a high-purity steroidal glycoside derivative, serving as a critical advanced intermediate in pharmaceutical synthesis. Its complex, defined stereochemistry makes it an essential building block for the development of novel therapeutic agents, particularly in the steroid and hormone analog space. This compound is primarily sought by research institutions and pharmaceutical manufacturers engaged in the development of next-generation drugs targeting metabolic and endocrine pathways.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel steroid-based active pharmaceutical ingredients (APIs).
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and the discovery of new drug candidates.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Biochemical Research: Employed in studies investigating steroid receptor interactions and metabolic pathways.
• Process Chemistry: Utilized in the scale-up and optimization of synthetic routes for complex steroidal molecules.

Basic Information

Product Name	(2S,3S,4S,5R,6S)-6-[[(10R,13S)-10,13-Dimethyl-17-Oxo-1,2,7,8,9,11,12,14,15,16-Decahydrocyclopenta[A]Phenanthren-3-Yl]Oxy]-3,4,5-Trihydroxy-Oxane-2-Carboxylic Acid
CAS No.	7649-05-0
Molecular Formula	C26H36O8
Molecular Weight	476.56 g/mol
Synonyms	3β-Hydroxy-5-androsten-17-one 3-glucuronide; Etiocholanolone Glucuronide; 17-Oxoandrostane-3α-yl β-D-Glucopyranosiduronic Acid; Androsterone Glucuronide (related isomer); Steroid D-Glucuronide; 5β-Androstan-3α-ol-17-one glucuronide; Etiocholanolone 3α-D-Glucuronide; 3α-Hydroxy-5β-androstan-17-one 3-glucuronide
EINECS	Contact for details

Quality Control

Our (2S,3S,4S,5R,6S)-6-[[(10R,13S)-10,13-Dimethyl-17-Oxo-1,2,7,8,9,11,12,14,15,16-Decahydrocyclopenta[A]Phenanthren-3-Yl]Oxy]-3,4,5-Trihydroxy-Oxane-2-Carboxylic Acid is produced under a strict quality management system. Every batch is subjected to comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the exacting standards required for pharmaceutical R&D and synthesis. Certificates of Analysis (COA) detailing all specifications and test results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. Long-term storage under inert atmosphere is recommended for optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.