Description

Z-Gly-Gly-Gly-Gly-Gly-Gly-Oh CAS NO 7598-84-7 is a synthetic hexaglycine peptide derivative featuring a benzyloxycarbonyl (Z) N-terminal protecting group and a free carboxylic acid C-terminus. This compound serves as a crucial building block and model substrate in advanced peptide synthesis and biochemical research. It is primarily utilized by pharmaceutical R&D laboratories, biotechnology companies, and academic research institutions for studying enzyme kinetics, developing novel peptide-based therapeutics, and calibrating analytical instrumentation.

Application

• Peptide Synthesis Intermediate: Used as a protected peptide fragment for the solid-phase or solution-phase synthesis of longer, more complex polypeptides.
• Enzymology Research: Acts as a standardized substrate for investigating the activity, specificity, and inhibition of proteolytic enzymes like peptidases and proteases.
• Biochemical Assay Development: Serves as a reference standard or calibrant in HPLC, LC-MS, and other analytical methods for peptide quantification and purity analysis.
• Structure-Activity Relationship (SAR) Studies: Provides a well-defined oligoglycine backbone for modifying side chains to explore peptide function and receptor binding.
• Material Science & Biomaterials: Investigated for its potential in creating peptide-based hydrogels, surface coatings, and other bio-compatible materials.

Basic Information

Item	Detail
Product Name	Z-Gly-Gly-Gly-Gly-Gly-Gly-Oh
CAS No.	7598-84-7
Molecular Formula	C26H38N8O9
Molecular Weight	606.63 g/mol
Synonyms	Nα-Benzyloxycarbonyl-hexaglycine; Z-Hexaglycine-OH; Z-GGGGGG-OH; Benzyloxycarbonyl-glycyl-glycyl-glycyl-glycyl-glycyl-glycine; N-Cbz-hexaglycine; Cbz-Gly-Gly-Gly-Gly-Gly-Gly-OH; Nα-Carbobenzoxy-hexaglycine; Hexaglycine, N-benzyloxycarbonyl-
EINECS	Contact for details

Quality Control

Our Z-Gly-Gly-Gly-Gly-Gly-Gly-Oh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity verification and spectroscopic identification (NMR, MS), to ensure it meets exacting research-grade specifications. Certificates of Analysis (COA) with detailed chromatographic and spectral data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions at -20°C.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.