Description

5-(2-Amino-1,3-Thiazol-4-Yl)-1H-Pyrimidine-2,4-Dione is a heterocyclic organic compound featuring a fused thiazole-pyrimidine-dione structure, serving as a critical synthetic intermediate. This compound is valued for its role in constructing complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs). It is primarily needed by research institutions and manufacturers in the pharmaceutical and agrochemical sectors engaged in nucleoside analog synthesis and medicinal chemistry programs.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel antiviral and anticancer nucleoside analogs.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new drug candidates.
• Agrochemical Development: Serves as a precursor in the creation of new herbicides and fungicides with specific modes of action.
• Biochemical Research: Utilized in studies involving enzyme inhibition and as a substrate analog in biochemical assays.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for bespoke chemical synthesis projects.

Basic Information

Product Name	5-(2-Amino-1,3-Thiazol-4-Yl)-1H-Pyrimidine-2,4-Dione
CAS No.	7597-80-0
Molecular Formula	C7H6N4O2S
Molecular Weight	210.21 g/mol
Synonyms	5-(2-Aminothiazol-4-yl)uracil; 5-(2-Amino-4-thiazolyl)uracil; 5-(2-Amino-1,3-thiazol-4-yl)pyrimidine-2,4(1H,3H)-dione; 5-(2-Amino-4-thiazolyl)-2,4(1H,3H)-pyrimidinedione; 2,4-Dioxo-5-(2-amino-4-thiazolyl)-1,2,3,4-tetrahydropyrimidine; 5-(2-Amino-thiazol-4-yl)-1H-pyrimidin-2,4-dione; 7597-80-0
EINECS	Contact for details

Quality Control

Our 5-(2-Amino-1,3-Thiazol-4-Yl)-1H-Pyrimidine-2,4-Dione is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure compliance with research and development grade standards. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to ensure stability.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.