Description

H-D-Trp-Oet Hcl is a high-purity, protected amino acid derivative essential for advanced peptide synthesis. This compound serves as a critical chiral building block, enabling the precise construction of complex peptides and peptidomimetics with specific biological activities. It is primarily utilized by research institutions and pharmaceutical companies engaged in drug discovery, development of therapeutic peptides, and biochemical research.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key protected intermediate for the controlled incorporation of the D-tryptophan residue into peptide chains.
• Pharmaceutical Research & Development: Used in the discovery and synthesis of novel peptide-based drug candidates, including hormone analogs and receptor-targeting molecules.
• Bioconjugation & Labeling: Acts as a precursor for creating fluorescently labeled or biotinylated peptides for diagnostic and imaging applications.
• Academic & Biochemical Research: Employed in studies of enzyme-substrate interactions, protein folding, and structure-activity relationships (SAR).
• Process Development: Serves as a reference standard and starting material for scaling up GMP-grade peptide APIs (Active Pharmaceutical Ingredients).

Basic Information

Product Name	H-D-Trp-Oet Hcl
CAS No.	7479-05-2
Molecular Formula	C₁₃H₁₇ClN₂O₂
Molecular Weight	268.74 g/mol
Synonyms	D-Tryptophan ethyl ester hydrochloride; (R)-2-Amino-3-(1H-indol-3-yl)propanoic acid ethyl ester hydrochloride; Ethyl D-tryptophanate hydrochloride; H-D-Trp-OEt·HCl; D-Trp-OEt HCl; Ethyl (R)-2-amino-3-(1H-indol-3-yl)propanoate hydrochloride
EINECS	Contact for details

Quality Control

Our H-D-Trp-Oet Hcl is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and identity confirmation via IR and NMR spectroscopy. We provide full traceability and Certificates of Analysis (COA) are available for all shipments to ensure compliance with your research and development protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee (D-isomer)
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.