Description

4-Amino-2-Chloropyrimidine is a versatile heterocyclic building block of significant importance in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of various drug candidates, particularly those targeting kinase inhibition and other biological pathways.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, contributing to crop protection solutions.
• Chemical Research & Development: Serves as a fundamental scaffold for medicinal chemistry and material science research.
• API Manufacturing: Employed in the multi-step synthesis of complex Active Pharmaceutical Ingredients (APIs).
• Ligand and Catalyst Development: Useful for creating specialized ligands and organocatalysts used in asymmetric synthesis.
• Dye and Pigment Intermediate: Can be utilized in the synthesis of certain heterocyclic dyes and functional materials.

Basic Information

Item	Detail
Product Name	4-Amino-2-Chloropyrimidine
CAS No.	7461-50-9
Molecular Formula	C4H4ClN3
Molecular Weight	129.55 g/mol
Synonyms	2-Chloro-4-pyrimidinamine; 2-Chloro-4-aminopyrimidine; 4-Amino-2-chloropyrimidine; 2-Chloropyrimidin-4-amine; 4-Pyrimidinamine, 2-chloro-; 4-Amino-2-chloro-pyrimidine; 2-Chloro-4-pyrimidinylamine
EINECS	Contact for details

Quality Control

Our 4-Amino-2-Chloropyrimidine is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request for quality assurance and regulatory compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.