Description

Diglycyl-Histidine is a high-purity, synthetic dipeptide derivative of the essential amino acid histidine. This compound is valued for its role as a biochemical building block and a potential precursor in advanced peptide synthesis. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and biotechnology sectors for applications in drug discovery, proteomics, and as a standard in analytical chemistry.

Application

• Pharmaceutical Research & Development: Serves as a key intermediate or reference standard in the synthesis and study of novel peptide-based therapeutics and enzyme inhibitors.
• Biochemical Reagent: Used as a substrate or model compound in enzymatic studies and metabolic pathway research.
• Proteomics & Peptide Synthesis: Acts as a building block in solid-phase peptide synthesis (SPPS) for creating custom peptides and protein fragments.
• Cosmetic & Dermatological Formulations: Investigated for potential use in anti-aging and skin-care products due to its peptide structure.
• Nutritional Science: Studied for its potential bioactive properties and role in specialized nutraceutical applications.
• Analytical Chemistry: Employed as a high-purity calibration standard in chromatographic (HPLC, LC-MS) analyses.

Basic Information

Product Name	Diglycyl-Histidine
CAS No.	7451-76-5
Molecular Formula	C11H16N6O4
Molecular Weight	296.28 g/mol
Synonyms	Gly-Gly-His; H-Gly-Gly-His-OH; L-Histidyl-diglycine; N-(N-Glycylglycyl)-L-histidine; Diglycyl-L-histidine; GGH; His-Gly-Gly; Glycylglycylhistidine
EINECS	Contact for details

Quality Control

Our Diglycyl-Histidine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and residual solvent screening, to ensure it meets the stringent requirements of research and development applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled in a low-humidity environment to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation	-20° to -25° (c=1 in H2O)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.