Description

Cyclo(-Gly-Trp) is a synthetic cyclic dipeptide, also known as a diketopiperazine (DKP), formed from the amino acids glycine and L-tryptophan. This compound is of significant interest in pharmaceutical research and development due to its role as a key structural motif and potential pharmacophore. It serves as a valuable building block and intermediate for medicinal chemists, peptide scientists, and researchers in the life sciences sector.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of more complex peptide-based drugs and bioactive molecules.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and as a scaffold for developing new therapeutic agents.
• Biochemical Research: Serves as a reference standard or probe in studies of enzyme inhibition, receptor binding, and signal transduction pathways.
• Peptide Synthesis: Acts as a protected dipeptide unit or a conformational constraint element in solid-phase and solution-phase peptide synthesis.
• Cosmetic Peptide Precursor: Investigated for potential use in the development of advanced anti-aging or skin-care active ingredients.

Basic Information

Product Name	Cyclo(-Gly-Trp)
CAS No.	7451-73-2
Molecular Formula	C13H13N3O2
Molecular Weight	243.26 g/mol
Synonyms	Cyclo(glycyl-L-tryptophyl); Glycyl-L-tryptophan anhydride; 3-(1H-Indol-3-ylmethyl)-2,5-piperazinedione; Cyclo(Gly-Trp); L-Tryptophylglycine anhydride; DKPs; Diketopiperazine; 2,5-Diketopiperazine derivative
EINECS	Contact for details

Quality Control

Our Cyclo(-Gly-Trp) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.