Description

n-α-Methyl-L-Lysinehydrochloride CAS NO 7431-89-2 is a high-purity, non-proteinogenic amino acid derivative, specifically the hydrochloride salt of the methylated lysine analog. This compound serves as a critical building block and research tool in advanced pharmaceutical development and biochemical research. It is primarily utilized by research institutions and pharmaceutical companies engaged in peptide synthesis, enzyme inhibition studies, and the investigation of epigenetic mechanisms.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel peptide-based therapeutics and protease inhibitors.
• Biochemical Research: Used as a substrate analog or inhibitor in enzymatic studies, particularly for lysine-specific enzymes like methyltransferases and demethylases.
• Peptide Chemistry: Incorporated into custom peptides to study structure-activity relationships (SAR) and to modulate peptide stability and bioavailability.
• Epigenetics Research: Serves as a tool compound to investigate histone modification and protein methylation pathways.
• Standards & References: Employed as a certified reference material (CRM) or analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	n-α-Methyl-L-Lysinehydrochloride
CAS No.	7431-89-2
Molecular Formula	C7H17ClN2O2
Molecular Weight	196.68 g/mol
Synonyms	Nα-Methyl-L-lysine hydrochloride; (S)-2-Amino-6-(methylamino)hexanoic acid hydrochloride; α-Methyl-L-lysine HCl; L-α-Methyllysine hydrochloride; 2-Amino-6-(methylamino)caproic acid hydrochloride; N-Methyl-L-lysine monohydrochloride; N6-Methyl-L-lysine hydrochloride (Note: common misassignment, correct isomer is Nα-methyl)
EINECS	Contact for details

Quality Control

Our n-α-Methyl-L-Lysinehydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC for purity, chiral analysis for enantiomeric excess, and identity confirmation via IR and NMR. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with research and development grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity. Avoid prolonged exposure to air during handling.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.