Description

2-Hydroxy-3-Phenyl-L-Alanine is a non-proteinogenic amino acid derivative of L-phenylalanine, featuring a hydroxyl group on the β-carbon of the phenylalanine side chain. This structural modification makes it a valuable chiral building block and intermediate in advanced organic synthesis and pharmaceutical research. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors for developing novel compounds and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and development of novel drug candidates, particularly in neuroscience and metabolic disorder research.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies to investigate tyrosine and phenylalanine metabolism pathways.
• Peptide Synthesis: Incorporation into custom peptides to study structure-activity relationships (SAR) and to create peptides with modified properties.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical and academic laboratories.
• Fine Chemical Synthesis: A versatile starting material for the synthesis of more complex, functionalized organic molecules in medicinal chemistry.

Basic Information

Product Name	2-Hydroxy-3-Phenyl-L-Alanine
CAS No.	7423-92-9
Molecular Formula	C9H11NO3
Molecular Weight	181.19 g/mol
Synonyms	L-3-(2-Hydroxyphenyl)alanine; (2S)-2-Amino-3-(2-hydroxyphenyl)propanoic acid; β-2-Hydroxy-L-phenylalanine; 2-Hydroxy-L-phenylalanine; 2-OH-L-Phe; 2-Hydroxyphenylalanine; L-2-Hydroxyphenylalanine; 3-(2-Hydroxyphenyl)-L-alanine
EINECS	Contact for details

Quality Control

Our 2-Hydroxy-3-Phenyl-L-Alanine is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) detailing all test results are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after use to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation	[α]20/D: Specific range provided on COA
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.