Description

Pyrimido[4,5-d]pyrimidin-4(3H)-one (6Ci,8Ci) is a high-purity heterocyclic organic compound that serves as a critical advanced intermediate in pharmaceutical research and development. Its unique fused pyrimidine core structure makes it a valuable building block for synthesizing novel drug candidates, particularly in oncology and antiviral therapeutic areas. This compound is essential for medicinal chemists and R&D laboratories focused on developing next-generation small molecule therapies.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of potential kinase inhibitors and other targeted therapeutic agents.
• Medicinal Chemistry Research: Used as a core scaffold in structure-activity relationship (SAR) studies and lead optimization programs.
• Biochemical Tool Compound: Serves as a reference standard or starting material for developing biochemical probes and assay components.
• Academic & Contract Research: Employed in university and CRO settings for exploratory research into novel heterocyclic chemistry and bioactivity.
• Process Chemistry Development: Used in scaling up synthetic routes for active pharmaceutical ingredients (APIs) under GMP-like conditions.

Basic Information

Product Name	Pyrimido[4,5-d]pyrimidin-4(3H)-one (6Ci,8Ci)
CAS No.	7403-26-1
Molecular Formula	C6H4N4O
Molecular Weight	148.12 g/mol
Synonyms	4(3H)-Pyrimido[4,5-d]pyrimidinone; 4-Hydroxypyrimido[4,5-d]pyrimidine; Pyrimido[4,5-d]pyrimidin-4-ol; 1H-Pyrimido[4,5-d]pyrimidin-4-one; 4-Oxo-3,4-dihydropyrimido[4,5-d]pyrimidine; 4-Pyrimidopyrimidinone; 7403-26-1 (CAS RN)
EINECS	Contact for details

Quality Control

Our Pyrimido[4,5-d]pyrimidin-4(3H)-one is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including HPLC purity, NMR, and mass spectrometry confirmation. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is supplied with every shipment to support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.