Description

H-Cys-Onam Hcl CAS NO 7319-37-1 is a protected cysteine derivative, specifically the hydrochloride salt of N-(9H-fluoren-9-ylmethoxycarbonyl)-S-trityl-L-cysteine. This compound is a critical building block in solid-phase peptide synthesis (SPPS), enabling the controlled introduction of cysteine residues while preventing unwanted side reactions. It is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors developing therapeutic peptides, diagnostic agents, and biochemical tools.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key protected amino acid derivative for the sequential assembly of peptide chains on resin.
• Pharmaceutical Intermediates: Used in the research and production of peptide-based drugs, including hormones, enzyme inhibitors, and antimicrobial peptides.
• Bioconjugation Chemistry: Serves as a precursor for introducing thiol groups for site-specific labeling or cross-linking with proteins and other biomolecules.
• Research & Development: A vital reagent in academic and industrial labs for studying protein structure, function, and peptide mimetics.
• Combinatorial Chemistry Libraries: Employed in the generation of diverse peptide libraries for drug discovery and screening.

Basic Information

Product Name	H-Cys-Onam Hcl
CAS No.	7319-37-1
Molecular Formula	C32H30NO4S • HCl
Molecular Weight	552.11 g/mol
Synonyms	Fmoc-Cys(Trt)-OH • HCl; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-S-trityl-L-cysteine hydrochloride; Fmoc-S-trityl-L-cysteine hydrochloride; Fmoc-Cys(Trt)-OH hydrochloride; Fmoc-Cysteine(Trt)-OH • HCl; Nα-Fmoc-S-trityl-L-cysteine hydrochloride; (2R)-2-[(9H-Fluoren-9-ylmethoxy)carbonylamino]-3-[tritylsulfanyl]propanoic acid hydrochloride
EINECS	Contact for details

Quality Control

Our H-Cys-Onam Hcl is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation, to ensure it meets the high standards required for peptide synthesis. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and purity. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Optical Rotation [α]D20	Contact for details
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.