Description

Nα-Acetyl-5-Fluoro-D,L-Tryptophan is a chemically modified derivative of the essential amino acid tryptophan, featuring acetylation at the α-amino group and fluorination at the 5-position of the indole ring. This structural modification enhances its metabolic stability and makes it a valuable non-natural amino acid building block for advanced research and development. It is primarily utilized by pharmaceutical R&D teams, peptide synthesis specialists, and agrochemical researchers. The compound is offered in high-purity grades suitable for demanding synthetic applications.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel peptide-based therapeutics and bioactive molecules.
• Peptide Synthesis: Serves as a protected amino acid derivative in solid-phase and solution-phase peptide synthesis, particularly for incorporating fluorinated tryptophan analogs.
• Biochemical Research: Used in enzymatic studies and as a probe to investigate protein structure, function, and fluorescence quenching mechanisms due to the fluorine atom.
• Agrochemical Development: Acts as a precursor in the synthesis of advanced crop protection agents and plant growth regulators.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	Nα-Acetyl-5-Fluoro-D,L-Tryptophan
CAS No.	7303-54-0
Molecular Formula	C₁₃H₁₃FN₂O₃
Molecular Weight	264.25 g/mol
Synonyms	5-Fluoro-N-acetyl-DL-tryptophan; Ac-5-F-DL-Trp-OH; N-Acetyl-5-fluoro-DL-tryptophan; (RS)-2-Acetamido-3-(5-fluoro-1H-indol-3-yl)propanoic acid; 2-Acetylamino-3-(5-fluoroindol-3-yl)propionic acid; DL-5-Fluorotryptophan N-acetate; N-Acetyl-5-fluorotryptophan; Nα-Acetyl-5-fluorotryptophan
EINECS	Contact for details

Quality Control

Every batch of Nα-Acetyl-5-Fluoro-D,L-Tryptophan is manufactured under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all test results are provided with each shipment and are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.