Description

L-Glutamic Acid γ-(4-Nitroanilide) CAS NO 7300-59-6 is a specialized chromogenic substrate widely used in enzymatic assays and biochemical research. Its core value lies in its high sensitivity and specificity for detecting protease activity, particularly that of γ-glutamyl transpeptidase (GGT). This compound is essential for researchers and quality control laboratories in the pharmaceutical, diagnostic, and life science industries who require reliable tools for enzyme kinetics, diagnostic kit development, and biochemical pathway analysis.

Application

• Enzymatic Assay Substrate: Primary substrate for the colorimetric and spectrophotometric determination of γ-glutamyl transpeptidase (GGT) activity in clinical and research settings.
• Diagnostic Reagent Manufacturing: A key component in the production of clinical diagnostic kits for liver function tests and other medical diagnostics.
• Biochemical Research: Used in studying enzyme kinetics, inhibition, and the role of GGT in various physiological and pathological processes, including oxidative stress and cancer.
• Pharmaceutical Development: Employed in high-throughput screening (HTS) for identifying and characterizing potential GGT inhibitors as therapeutic agents.
• Quality Control (QC) Testing: Serves as a reference standard and critical reagent in QC laboratories for validating assay performance and ensuring batch-to-b consistency in diagnostic manufacturing.

Basic Information

Product Name	L-Glutamic Acid γ-(4-Nitroanilide)
CAS No.	7300-59-6
Molecular Formula	C₁₁H₁₃N₃O₆
Molecular Weight	283.24 g/mol
Synonyms	L-γ-Glutamyl-4-nitroanilide; γ-L-Glutamyl-4-nitroanilide; 4-Nitroanilide of L-Glutamic Acid; GGPNA; L-Glutamic Acid γ-(4-Nitroanilide); Glutamyl-4-nitroanilide; GGT Substrate; N-(4-Nitrophenyl)-L-glutamine
EINECS	Contact for details

Quality Control

Our L-Glutamic Acid γ-(4-Nitroanilide) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, identity confirmation by IR spectroscopy, and loss on drying analysis, to ensure it meets high-purity standards suitable for research and diagnostic applications. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Yellow to orange-yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Solubility	Soluble in DMSO, DMF; slightly soluble in water
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.