Description

Cyclo(Leucyl-Phenylalanyl) CAS NO 7280-77-5 is a synthetic cyclic dipeptide, also known as a diketopiperazine (DKP), formed from the amino acids L-leucine and L-phenylalanine. This compound serves as a crucial pharmacophore and building block in medicinal chemistry and advanced material science. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical synthesis sectors for developing novel therapeutic agents and functional biomaterials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of more complex peptide-based drugs and protease inhibitors.
• Medicinal Chemistry Research: Used as a core scaffold in drug discovery programs to explore structure-activity relationships (SAR) and develop new bioactive molecules.
• Bioconjugation & Probe Development: Serves as a linker or spacer in the creation of biochemical probes, diagnostic agents, and targeted drug delivery systems.
• Material Science: Investigated for its self-assembly properties in the development of novel nanomaterials and hydrogels.
• Cosmetic & Personal Care: Potential use in advanced skincare formulations for its peptide-based bioactivity.
• Academic & Industrial R&D: A standard reagent for studying cyclic peptide conformations, stability, and biological interactions.

Basic Information

Product Name	Cyclo(Leucyl-Phenylalanyl)
CAS No.	7280-77-5
Molecular Formula	C15H20N2O2
Molecular Weight	260.33 g/mol
Synonyms	Cyclo(L-Leucyl-L-phenylalanyl); L-Leucyl-L-phenylalanine anhydride; 3-Benzyl-6-isobutyl-2,5-piperazinedione; Cyclo(Leu-Phe); c(Leu-Phe); Diketopiperazine (Leu-Phe); 2,5-Diketopiperazine derivative of Leu and Phe; L-Leucyl-L-phenylalanine cyclic dipeptide
EINECS	Contact for details

Quality Control

Our Cyclo(Leucyl-Phenylalanyl) is produced under stringent conditions to ensure high purity and batch-to-batch consistency. Quality is verified through a comprehensive suite of analytical techniques including HPLC, NMR, and mass spectrometry. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each batch. We adhere to cGMP principles where applicable to support our clients in regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant use and inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.