Description

16-Acetylgitoxin is a chemically modified cardiac glycoside derivative, specifically an acetylated form of gitoxin. This compound is of significant interest in pharmaceutical research and development due to its potential as a precursor or intermediate in the synthesis of specialized cardiovascular agents. It is primarily utilized by research institutions, pharmaceutical manufacturers, and fine chemical suppliers engaged in the development of novel therapeutic compounds or analytical reference standards. The product is supplied under the identifier CAS 7242-07-1.

Application

• Pharmaceutical Intermediate: Key starting material or intermediate in the research and synthesis of novel cardiac glycoside derivatives and related therapeutic agents.
• Biochemical Research: Used as a reference standard or probe in pharmacological studies to investigate the structure-activity relationships (SAR) of digitalis-like compounds.
• Analytical Standard: Serves as a high-purity certified reference material (CRM) for quality control and method development in analytical laboratories (e.g., HPLC, LC-MS).
• Academic Research: Employed in university and institutional labs for studying the metabolism, pharmacokinetics, and toxicology of cardiac glycosides.
• Process Development: Used in scaling up and optimizing synthetic routes for advanced pharmaceutical ingredients (APIs) within regulated environments.

Basic Information

Product Name	16-Acetylgitoxin
CAS No.	7242-07-1
Molecular Formula	C₄₃H₆₆O₁₄
Molecular Weight	807.0 g/mol
Synonyms	16-Acetyl Gitoxin; 16-Acetyl-3β-[(O-2,6-dideoxy-β-D-ribo-hexopyranosyl-(1→4)-O-2,6-dideoxy-β-D-ribo-hexopyranosyl-(1→4)-2,6-dideoxy-β-D-ribo-hexopyranosyl)oxy]-14-hydroxy-19-oxocard-20(22)-enolide; 16-Acetyl-3β-[(O-β-D-digitoxosyl-(1→4)-O-β-D-digitoxosyl-(1→4)-β-D-digitoxosyl)oxy]-14-hydroxy-19-oxocard-20(22)-enolide; Acetylgitoxin; Gitoxin 16-acetate
EINECS	Contact for details

Quality Control

Our 16-Acetylgitoxin is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles, typically determined by advanced chromatographic methods. We support research and development needs with materials suitable for use under current Good Manufacturing Practice (cGMP) guidelines for non-clinical development stages.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.