Description

Isothiazolo[4,3-D]Pyrimidine (8Ci,9Ci) is a high-purity fused heterocyclic compound, serving as a critical advanced intermediate in modern organic synthesis. Its unique bicyclic structure, incorporating both isothiazole and pyrimidine rings, makes it a valuable building block for the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. This compound is primarily sought by research institutions and industrial R&D departments focused on medicinal chemistry, material science, and crop protection.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for antiviral, anticancer, and anti-inflammatory therapeutic areas.
• Agrochemical Research: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging its heterocyclic scaffold for bioactivity.
• Material Science: Serves as a building block for creating specialized organic electronic materials, ligands for catalysis, and photoactive compounds.
• Academic & Contract Research: Essential for method development and structure-activity relationship (SAR) studies in synthetic organic chemistry laboratories.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and target identification.

Basic Information

Product Name	Isothiazolo[4,3-D]Pyrimidine (8Ci,9Ci)
CAS No.	7130-83-8
Molecular Formula	C5H3N3S
Molecular Weight	137.16 g/mol
Synonyms	Isothiazolo[4,3-d]pyrimidine; 1,2,3-Benzisothiazole, 4,7-dihydro- (8CI,9CI); 4,7-Dihydroisothiazolo[4,3-d]pyrimidine; Isothiazolo(4,3-d)pyrimidine; 4H-Isothiazolo[4,3-d]pyrimidine; NSC 221986; AS-81033
EINECS	Contact for details

Quality Control

Our Isothiazolo[4,3-D]Pyrimidine (8Ci,9Ci) is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the stringent requirements for research and development applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.