Description

Isothiazolo[4,5-D]Pyrimidine (8Ci,9Ci) CAS NO 7078-51-5 is a high-value heterocyclic organic compound featuring a fused isothiazole and pyrimidine ring system. This unique molecular architecture makes it a critical advanced pharmaceutical intermediate and a versatile scaffold in medicinal chemistry research. It is primarily sought after by R&D and production teams in the pharmaceutical and agrochemical sectors for developing novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of potential drug candidates, particularly for antiviral, anticancer, and anti-inflammatory therapies.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Agrochemical Development: Acts as a precursor in the research and synthesis of new-generation herbicides, fungicides, and insecticides.
• Chemical Biology Probe: Utilized in biochemical assays to study enzyme inhibition and protein-ligand interactions.
• Material Science Research: Investigated as a precursor for specialty polymers or organic electronic materials due to its heterocyclic structure.

Basic Information

Product Name	Isothiazolo[4,5-D]Pyrimidine (8Ci,9Ci)
CAS No.	7078-51-5
Molecular Formula	C5H3N3S
Molecular Weight	137.16 g/mol
Synonyms	Isothiazolo[4,5-d]pyrimidine; 1,2,3-Thiadiazolo[5,4-d]pyrimidine; [1,2,3]Thiadiazolo[5,4-d]pyrimidine; 1λ⁴,2,3-Thiadiazolo[5,4-d]pyrimidine; Thiadiazolo[5,4-d]pyrimidine; Isothiazolo(4,5-d)pyrimidine; 8CI,9CI-Isothiazolo[4,5-d]pyrimidine
EINECS	Contact for details

Quality Control

Our Isothiazolo[4,5-D]Pyrimidine is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality system is designed to meet the stringent requirements of GMP environments for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.