Description

4-Chloro-6-Cyclopropylpyrimidine (Saltdata: Free) is a high-purity, versatile pyrimidine derivative serving as a critical building block in advanced organic synthesis. Its value lies in its reactive chloro and cyclopropyl groups, which enable the construction of complex molecular architectures with specific functionalities. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), especially in kinase inhibitor and antiviral drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides, leveraging the biological activity of the pyrimidine core.
• Material Science Research: Serves as a precursor for creating specialized ligands, functionalized polymers, and other advanced materials.
• Chemical Biology: Employed in the synthesis of molecular probes and tool compounds for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis projects requiring precise functionalization of the pyrimidine ring system.

Basic Information

Product Name	4-Chloro-6-Cyclopropylpyrimidine (Saltdata: Free)
CAS No.	7038-76-8
Molecular Formula	C7H7ClN2
Molecular Weight	154.60 g/mol
Synonyms	4-Chloro-6-cyclopropylpyrimidine; 6-Cyclopropyl-4-chloropyrimidine; 4-Chloro-6-cyclopropyl-pyrimidine; 4-Chloro-6-cyclopropyl-1,3-diazine; Pyrimidine, 4-chloro-6-cyclopropyl-; 4-Chloro-6-(cyclopropyl)pyrimidine; 4-Chloro-6-cyclopropyl-1,3-diazine
EINECS	Contact for details

Quality Control

Our 4-Chloro-6-Cyclopropylpyrimidine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to verify identity, potency, and impurity profiles. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment, supporting your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Maximum Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.