Description

4,6-Dichloro-n-Methyl-n-Phenylpyrimidin-2-Amine is a high-purity, halogenated pyrimidine derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs) and agrochemicals, where its specific substitution pattern enables precise molecular modifications. It is primarily sought by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for the synthesis of novel compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of novel drug candidates, particularly in kinase inhibitor and antiviral agent synthesis.
• Agrochemical Synthesis: Used as a precursor in the manufacture of advanced herbicides, fungicides, and plant growth regulators.
• Organic Synthesis Building Block: Employed in cross-coupling reactions, nucleophilic substitutions, and other transformations to construct complex heterocyclic systems.
• Material Science Research: Investigated as a monomer or functional component in the development of specialty polymers and organic electronic materials.
• Chemical Research & Development: Serves as a standard or starting material in academic and industrial R&D labs for methodological studies and library synthesis.

Basic Information

Product Name	4,6-Dichloro-n-Methyl-n-Phenylpyrimidin-2-Amine
CAS No.	7038-66-6
Molecular Formula	C11H9Cl2N3
Molecular Weight	254.11 g/mol
Synonyms	4,6-Dichloro-N-methyl-N-phenyl-2-pyrimidinamine; 2-Amino-4,6-dichloro-N-methyl-N-phenylpyrimidine; N-Methyl-N-phenyl-4,6-dichloropyrimidin-2-amine; 4,6-Dichloro-2-(N-methylanilino)pyrimidine; 7038-66-6; 4,6-Dichloro-N-methyl-N-phenylpyrimidin-2-amine
EINECS	Contact for details

Quality Control

Our 4,6-Dichloro-n-Methyl-n-Phenylpyrimidin-2-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment ensures the material meets the stringent requirements for research and cGMP intermediate synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.