Description

2-Cyclopropylpyrimidine-4,6-Diol is a versatile heterocyclic building block characterized by its pyrimidine core substituted with a cyclopropyl group and two hydroxyl functionalities. This compound is valued for its role as a key synthetic intermediate in the development of complex organic molecules, particularly in the pharmaceutical and agrochemical sectors. It is primarily sought after by research chemists and process development scientists working on active pharmaceutical ingredients (APIs), crop protection agents, and advanced material precursors.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, antiviral agents, and enzyme inhibitors.
• Agrochemical Synthesis: Serves as a building block for developing new-generation herbicides, fungicides, and plant growth regulators with enhanced efficacy and selectivity.
• Chemical Research & Development: Used in academic and industrial R&D labs for exploring new heterocyclic chemistry, creating molecular libraries for screening, and developing novel synthetic methodologies.
• Material Science: Potential application as a monomer or functional additive in the synthesis of specialty polymers and advanced organic materials with specific electronic or photophysical properties.
• Ligand & Catalyst Development: The diol and pyrimidine structure can be utilized to create complexing agents or ligands for metal catalysis in asymmetric synthesis.

Basic Information

Product Name	2-Cyclopropylpyrimidine-4,6-Diol
CAS No.	7024-58-0
Molecular Formula	C7H8N2O2
Molecular Weight	152.15 g/mol
Synonyms	4,6-Dihydroxy-2-cyclopropylpyrimidine; 2-Cyclopropyl-4,6-pyrimidinediol; 4,6-Dihydroxy-2-cyclopropyl-1,3-diazine; Cyclopropylpyrimidine-4,6-diol; 2-Cyclopropyl-1H-pyrimidine-4,6-dione (tautomeric form); 2-Cyclopropyluracil (common name); 2-Cyclopropyl-4,6-dihydroxypyrimidine
EINECS	Contact for details

Quality Control

Our 2-Cyclopropylpyrimidine-4,6-Diol is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, which includes data from HPLC, NMR, and other relevant spectroscopic methods. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable supply and traceability for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent absorption of atmospheric moisture, which may affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.