Description

4-{[(1,3-Dimethyl-2,6-Dioxo-2,3,6,7-Tetrahydro-1H-Purin-8-Yl)Methyl]Amino}Benzoic Acid is a high-purity xanthine derivative designed for advanced research and pharmaceutical development. This compound serves as a critical building block and pharmacological reference standard in the synthesis of novel therapeutic agents. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing treatments for neurological and cardiovascular conditions.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of adenosine receptor antagonists and other xanthine-based active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a reference standard and tool compound in studies targeting adenosine A1, A2A, and A2B receptors.
• Medicinal Chemistry: Serves as a core scaffold for structure-activity relationship (SAR) studies to optimize drug potency and selectivity.
• Analytical Standard: High-purity grade material for use in HPLC, LC-MS, and NMR as a calibration standard for quantitative analysis.
• Preclinical Development: Employed in the formulation of candidate drugs for pharmacokinetic and pharmacodynamic evaluation.

Basic Information

Item	Details
Product Name	4-{[(1,3-Dimethyl-2,6-Dioxo-2,3,6,7-Tetrahydro-1H-Purin-8-Yl)Methyl]Amino}Benzoic Acid
CAS No.	7000-61-5
Molecular Formula	C15H15N5O4
Molecular Weight	329.31 g/mol
Synonyms	8-[(4-Carboxyanilino)methyl]-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione; 1,3-Dimethyl-8-[[(4-carboxyphenyl)amino]methyl]-3,7-dihydro-1H-purine-2,6-dione; Xanthine-8-acetic acid, 1,3-dimethyl-, 4-aminobenzoate; 4-((1,3-Dimethyl-2,6-dioxo-1,2,3,6-tetrahydro-7H-purin-8-yl)methylamino)benzoic acid; 8-[(4-Carboxy-phenylamino)-methyl]-1,3-dimethyl-3,7-dihydro-purine-2,6-dione
EINECS	Contact for details

Quality Control

Our 4-{[(1,3-Dimethyl-2,6-Dioxo-2,3,6,7-Tetrahydro-1H-Purin-8-Yl)Methyl]Amino}Benzoic Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. Certificates of Analysis (COA) detailing all test results are provided to ensure traceability and compliance with your research or cGMP starting material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.