Description

n-Carboxy Anhydride-n-Trifluoro Acetyl Lysine is a specialized, highly reactive amino acid derivative used in advanced peptide synthesis. This compound matters as a key building block for introducing the unique trifluoroacetyl-protected lysine residue, enabling precise control over peptide structure and function. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel peptide-based therapeutics, diagnostics, and biochemical tools.

Application

• Solid-Phase Peptide Synthesis (SPPS): As an activated amino acid derivative for the efficient, sequential construction of custom peptide chains.
• Peptide Drug Discovery: Incorporation into peptide libraries for screening biological activity and optimizing drug candidates.
• Bioconjugation & Labeling: Facilitating the site-specific attachment of probes, tags, or other molecules to peptides via the reactive anhydride moiety.
• Material Science: Synthesis of peptide-polymer hybrids or biomimetic materials requiring specific, engineered amino acid sequences.
• Biochemical Research: Production of standardized peptides for use as antigens, enzyme substrates, or receptor ligands in experimental assays.

Basic Information

Product Name	n-Carboxy Anhydride-n-Trifluoro Acetyl Lysine
CAS No.	787-87-1
Molecular Formula	C9H11F3N2O5
Molecular Weight	284.19 g/mol
Synonyms	NCA-Nε-TFA-L-Lysine; Nε-Trifluoroacetyl-L-lysine N-Carboxy Anhydride; TFA-Lys NCA; (S)-2,5-Dioxo-4-(5-(trifluoroacetamido)pentyl)oxazolidine; L-Lysine, N6-(trifluoroacetyl)-, N-carboxyanhydride; Nε-TFA-L-Lysine NCA; NCA of Nε-TFA-L-Lysine; α-Amino acid N-carboxyanhydride of Nε-TFA-L-lysine
EINECS	Contact for details

Quality Control

Our n-Carboxy Anhydride-n-Trifluoro Acetyl Lysine is produced and tested under strict quality management protocols to ensure batch-to-batch consistency and high purity, suitable for sensitive research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards for fine chemical and pharmaceutical intermediate manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be handled under anhydrous conditions to prevent decomposition. For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.