Description

2,5-Bis(Trifluoromethyl)Phenol is a high-value fluorinated phenolic compound, distinguished by its two trifluoromethyl groups which impart unique electronic and steric properties. This compound is a critical advanced intermediate for the synthesis of complex molecules in high-tech industries, offering enhanced lipophilicity and metabolic stability. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty materials sectors for developing novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting central nervous system (CNS) disorders and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and pesticides, where the fluorine atoms contribute to improved biological activity and environmental persistence.
• Liquid Crystal Materials: Serves as a core component in the production of fluorinated liquid crystals for advanced display technologies.
• Polymer & Resin Modifier: Incorporated into specialty polymers to enhance chemical resistance, thermal stability, and surface properties.
• Organic Synthesis Reagent: Utilized in cross-coupling reactions and as a precursor for ligands in catalysis due to its electron-withdrawing character.
• Electronic Chemicals: Acts as an intermediate in the manufacture of etchants and cleaning agents for the semiconductor industry.

Basic Information

Product Name	2,5-Bis(Trifluoromethyl)Phenol
CAS No.	779-88-4
Molecular Formula	C8H4F6O
Molecular Weight	230.11 g/mol
Synonyms	2,5-Bis(trifluoromethyl)phenol; 2-Hydroxy-1,4-bis(trifluoromethyl)benzene; Phenol, 2,5-bis(trifluoromethyl)-; 1-Hydroxy-2,5-bis(trifluoromethyl)benzene; α,α,α,α',α',α'-Hexafluoro-2,5-xylenol; 2,5-Di(trifluoromethyl)phenol
EINECS	212-300-7

Quality Control

Our 2,5-Bis(Trifluoromethyl)Phenol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for every shipment. Our quality commitment aligns with cGMP and ISO 9001 standards to meet the stringent requirements of our global clientele.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber-colored or stored in light-resistant secondary packaging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	48 - 52 °C
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.