Description

2-Hydroxy-2-[4-(Trifluoromethyl)Phenyl]Ethylamine is a versatile chiral building block and intermediate of significant interest in advanced organic synthesis. Its molecular structure, featuring a trifluoromethylphenyl group and an ethanolamine backbone, makes it a valuable precursor for the development of active pharmaceutical ingredients (APIs) and specialty chemicals. This compound is primarily sought by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and material science sectors for creating novel compounds with targeted properties.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates, particularly in central nervous system (CNS) and anti-inflammatory therapies.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the trifluoromethyl group can enhance biological activity and stability.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands and catalysts used in asymmetric synthesis, crucial for producing enantiomerically pure compounds.
• Material Science Research: Employed in the synthesis of specialty polymers and advanced organic materials with unique optical or electronic properties.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological systems and enzyme mechanisms.

Basic Information

Product Name	2-Hydroxy-2-[4-(Trifluoromethyl)Phenyl]Ethylamine
CAS No.	776-02-3
Molecular Formula	C9H10F3NO
Molecular Weight	205.18 g/mol
Synonyms	2-Amino-1-[4-(trifluoromethyl)phenyl]ethanol; 1-(4-Trifluoromethylphenyl)-2-aminoethanol; α-(Aminomethyl)-4-(trifluoromethyl)benzyl alcohol; 2-Hydroxy-2-(4-trifluoromethylphenyl)ethylamine; Norfenfluramine alcohol; 4-Trifluoromethylphenylethanolamine; 2-Amino-1-(4-trifluoromethylphenyl)ethan-1-ol
EINECS	Contact for details

Quality Control

Our 2-Hydroxy-2-[4-(Trifluoromethyl)Phenyl]Ethylamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral purity assessment, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee (Specific enantiomer available)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.