Description

Pentafluorophenol is a highly fluorinated phenolic compound with the CAS number 771-61-9, serving as a versatile and reactive building block in advanced chemical synthesis. Its unique structure, featuring five fluorine atoms on the aromatic ring, makes it an excellent leaving group and a key intermediate for creating complex molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, where it is used to develop active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for creating esters and ethers used in drug discovery and development.
• Agrochemical Synthesis: Employed in the manufacture of advanced pesticides, herbicides, and fungicides, where its fluorinated structure enhances biological activity and stability.
• Peptide Coupling Reagent: Acts as an activating agent in peptide synthesis, facilitating the formation of amide bonds between amino acids.
• Polymer Chemistry: Used as a monomer or modifier in the production of high-performance polymers, including fluoropolymers with enhanced chemical and thermal resistance.
• Liquid Crystal & OLED Materials: Serves as a building block for synthesizing fluorinated components used in electronic displays and organic light-emitting diodes.
• Derivatization Agent in Analytics: Utilized in gas chromatography and mass spectrometry for derivatizing compounds to improve their detection and analysis.

Basic Information

Product Name	Pentafluorophenol
CAS No.	771-61-9
Molecular Formula	C6HF5O
Molecular Weight	184.06 g/mol
Synonyms	Pentafluorophenol; 2,3,4,5,6-Pentafluorophenol; Perfluorophenol; PFP; Pentafluorohydroxybenzene; Pentafluorophenyl alcohol; NSC 8857; Phenol, pentafluoro-
EINECS	212-246-6

Quality Control

Our Pentafluorophenol is produced under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, supporting its use in regulated synthesis pathways.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong bases and oxidizing agents. Due to its light-sensitive nature, containers should be kept in opaque packaging or amber glass.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	34 - 38 °C
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.