Description

L-Leucine Hydrochloride is the hydrochloride salt form of the essential branched-chain amino acid L-Leucine. This high-purity derivative is critical for applications requiring enhanced solubility and stability in acidic formulations. It serves as a vital building block and intermediate in the pharmaceutical, nutraceutical, and biochemical research sectors. The compound is valued for its consistent quality and reliable performance in demanding synthesis and production processes.

Application

• Pharmaceutical Intermediates: Used as a key chiral building block in the synthesis of active pharmaceutical ingredients (APIs) and peptide drugs.
• Nutraceutical & Dietary Supplements: Incorporated into amino acid infusion solutions, sports nutrition products, and specialized medical nutrition formulas.
• Biochemical Research: Serves as a standard and reagent in microbiological media preparation, cell culture studies, and metabolic pathway research.
• Food & Flavor Enhancement: Functions as a flavor modifier and nutrient fortifier in certain food products and flavoring agents.
• Cosmetic & Personal Care: Utilized in the formulation of hair and skin care products for its conditioning and moisturizing properties.

Basic Information

Product Name	L-Leucine Hydrochloride
CAS No.	760-84-9
Molecular Formula	C6H14ClNO2
Molecular Weight	167.63 g/mol
Synonyms	L-2-Amino-4-methylpentanoic acid hydrochloride; (S)-2-Amino-4-methylpentanoic acid hydrochloride; Leucine hydrochloride; H-Leu-OH·HCl; (S)-Leucine hydrochloride; L-Leucine HCl; L-Leucine monohydrochloride
EINECS	212-082-2

Quality Control

Our L-Leucine Hydrochloride is manufactured under strict quality management systems. It is tested to meet high-purity standards suitable for pharmaceutical and nutritional applications, with specifications aligning with relevant pharmacopoeial guidelines. Certificates of Analysis (COA) documenting identity, purity, and specific impurity profiles are available for every batch upon request, ensuring full traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature. Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms
Assay (HPLC)	98.5% - 101.5%
Specific Rotation	+14.5° to +16.5° (c=4 in 6N HCl)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Chloride Content	20.0% - 21.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.