Description

3β,5,12β,14-Tetrahydroxy-19-Oxo-5β-Card-20(22)-Enolide is a high-purity, steroidal cardenolide compound of significant interest in advanced pharmaceutical research and development. This specialized intermediate is valued for its precise molecular structure, which serves as a critical scaffold for the synthesis of bioactive molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents, particularly in the fields of cardiology and oncology.

Application

• Pharmaceutical Intermediate: Serves as a key synthetic precursor for the development of novel cardiac glycosides and other steroidal drugs.
• Biochemical Research: Used as a reference standard or probe in studies investigating sodium-potassium ATPase (Na+/K+-ATPase) inhibition and related cellular mechanisms.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies to design and optimize new chemical entities with targeted biological activity.
• Academic Research: Utilized in university and institutional labs for fundamental research on steroidal biosynthesis and natural product chemistry.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-purity steroidal building blocks.

Basic Information

Product Name	3β,5,12β,14-Tetrahydroxy-19-Oxo-5β-Card-20(22)-Enolide
CAS No.	749-72-4
Molecular Formula	C₂₃H₃₄O₇
Molecular Weight	434.51 g/mol
Synonyms	19-Oxocardenolide; 3β,5,12β,14-Tetrahydroxy-19-oxo-5β-card-20(22)-enolide; 19-Oxocarden; 3β,5,12β,14-Tetrahydroxy-19-oxocard-20(22)-enolide; 19-Oxo-5β-card-20(22)-enolide-3β,5,12β,14-tetrol; Cardenolide derivative 749-72-4; 19-Oxo cardiac aglycone derivative
EINECS	Contact for details

Quality Control

Our 3β,5,12β,14-Tetrahydroxy-19-Oxo-5β-Card-20(22)-Enolide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the exacting standards required for research and pharmaceutical applications. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.