Description

n-Benzoyl-Gly-Phe is a synthetic dipeptide derivative, specifically N-Benzoylglycyl-L-phenylalanine, widely recognized in pharmaceutical and biochemical research. This compound serves as a crucial building block and intermediate in the synthesis of more complex peptides and enzyme substrates. It is primarily utilized by research institutions, pharmaceutical developers, and fine chemical manufacturers focused on protease inhibition studies and advanced organic synthesis.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of peptide-based drugs and active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a specific substrate or inhibitor in enzymatic studies, particularly for proteases like chymotrypsin.
• Organic Synthesis: Serves as a protected dipeptide unit for constructing longer peptide chains in solid-phase and solution-phase peptide synthesis.
• Reference Standard: Employed as a high-purity analytical standard in quality control laboratories for method development and validation.
• Academic Research: Utilized in universities and research institutes for studying peptide bond formation, stability, and degradation pathways.

Basic Information

Product Name	n-Benzoyl-Gly-Phe
CAS No.	744-59-2
Molecular Formula	C₁₈H₁₈N₂O₄
Molecular Weight	326.35 g/mol
Synonyms	N-Benzoylglycyl-L-phenylalanine; Benzoylglycylphenylalanine; Bz-Gly-Phe-OH; N-(Benzoylglycyl)-L-phenylalanine; NSC 3340; L-Phenylalanine, N-(N-benzoylglycyl)-; Chymotrypsin substrate; Bz-Gly-Phe
EINECS	212-041-9

Quality Control

Our n-Benzoyl-Gly-Phe is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC for purity, chiral analysis to confirm stereochemical integrity, and spectroscopic identification (IR, NMR). Certificates of Analysis (COA) detailing all specifications and test results are provided to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Optical Rotation	-15° to -25° (c=1 in DMF)
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.