Description

Tolperisone CAS NO 728-88-1 is a centrally acting muscle relaxant belonging to the chemical class of piperidine derivatives. This compound is a critical active pharmaceutical ingredient (API) valued for its efficacy in reducing muscle tone and spasticity without significant sedative effects. It is primarily required by pharmaceutical manufacturers and research institutions for the formulation of medications targeting musculoskeletal disorders, such as muscle spasms and back pain.

Application

• Pharmaceutical API: Primary use as the active ingredient in prescription muscle relaxant medications.
• Treatment of Spasticity: Formulated for conditions like multiple sclerosis, cerebral palsy, and spinal cord injuries.
• Musculoskeletal Pain Relief: Used in medications for acute back pain and other painful muscle contractures.
• Neurological Research: Serves as a reference standard and investigational compound in neurological and pharmacological studies.
• Generic Drug Manufacturing: Essential for producing cost-effective generic versions of branded muscle relaxants.
• Veterinary Medicine: Potential application in veterinary pharmaceuticals for managing muscle disorders in animals.

Basic Information

Product Name	Tolperisone
CAS No.	728-88-1
Molecular Formula	C16H23NO
Molecular Weight	245.36 g/mol
Synonyms	2,4'-Dimethyl-3-piperidinopropiophenone; Mydocalm; Mydetone; E-064; N-(2,6-Dimethylphenyl)-2-methyl-3-piperidin-1-ylpropanamide; Tolperison; Tolperisonum; Caspan
EINECS	211-979-2

Quality Control

Our Tolperisone is manufactured under strict quality management systems, ensuring compliance with ICH Q7 guidelines for active pharmaceutical ingredients. Each batch undergoes comprehensive analytical testing, including identification, assay, and impurity profiling via HPLC and GC. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming the product meets specified purity standards, typically ≥98.5%.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	98.5% - 101.0% (on anhydrous basis)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 1.0% Any single impurity ≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.