Description

H-Phe-Gly-Oh is a high-purity dipeptide derivative, specifically the C-terminal carboxylic acid of phenylalanylglycine. This compound serves as a crucial building block and key intermediate in advanced organic synthesis and peptide research. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors who require reliable, high-quality raw materials for drug discovery and development.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of more complex peptide-based active pharmaceutical ingredients (APIs) and drug candidates.
• Peptide Synthesis Building Block: Used in solid-phase and solution-phase peptide synthesis (SPPS) to construct longer peptide chains for research and therapeutic applications.
• Biochemical Research: Employed as a standard or substrate in enzymatic studies, metabolic pathway analysis, and proteomics research.
• Chemical Biology Tool: Utilized in the development of peptide conjugates, probes, and inhibitors for studying biological processes.
• Fine Chemical Production: Serves as a specialized intermediate in the manufacture of custom peptides, cosmetic peptides, and other high-value chemical products.

Basic Information

Product Name	H-Phe-Gly-Oh
CAS No.	721-90-4
Molecular Formula	C11H14N2O3
Molecular Weight	222.24 g/mol
Synonyms	Phenylalanylglycine; L-Phenylalanylglycine; Glycine, L-phenylalanyl-; H-Phe-Gly-OH; Phe-Gly; FG; N-(L-Phenylalanyl)glycine; 2-[[(2S)-2-amino-3-phenylpropanoyl]amino]acetic acid
EINECS	211-967-9

Quality Control

Our H-Phe-Gly-Oh is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, chiral analysis, and identity confirmation, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation	-30.0° to -35.0° (c=1 in AcOH)
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.2%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.