Description

2,6-Bis(Trifluoromethyl)Pyrimidin-4-Amine is a high-value fluorinated pyrimidine derivative, serving as a critical building block in advanced chemical synthesis. Its unique structure, featuring two trifluoromethyl groups, imparts significant electronic and steric properties that are highly sought after in the development of novel materials and active compounds. This intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to incorporate fluorine motifs for enhanced bioactivity, stability, and performance.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in antiviral, anticancer, and central nervous system (CNS) drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl groups improve lipophilicity and biological activity.
• Material Science Precursor: Employed in the synthesis of fluorinated polymers, liquid crystals, and electronic materials that require specific dielectric properties and chemical resistance.
• Organic Synthesis Building Block: Facilitates the construction of complex heterocyclic compounds in academic and industrial research settings due to its reactive amine and electron-deficient pyrimidine ring.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	2,6-Bis(Trifluoromethyl)Pyrimidin-4-Amine
CAS No.	717-61-3
Molecular Formula	C6H3F6N3
Molecular Weight	231.10 g/mol
Synonyms	4-Amino-2,6-bis(trifluoromethyl)pyrimidine; 2,6-Bis(trifluoromethyl)-4-pyrimidinamine; 4-Pyrimidinamine, 2,6-bis(trifluoromethyl)-; 2,6-Bis(trifluoromethyl)pyrimidin-4-ylamine; 2,6-Di(trifluoromethyl)pyrimidin-4-amine
EINECS	Contact for details

Quality Control

Our 2,6-Bis(Trifluoromethyl)Pyrimidin-4-Amine is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data, including HPLC purity, NMR, and IR confirmation, to support your R&D and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flames. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.