Description

6-Chloro-2-(trifluoromethyl)-4,5-pyrimidinediamine is a high-purity, halogenated pyrimidine derivative of significant interest in advanced chemical synthesis. This compound serves as a critical building block for the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where its unique trifluoromethyl and chloro substituents impart valuable properties to target molecules. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers engaged in creating next-generation therapeutics and crop protection agents.

Application

• Pharmaceutical Intermediate: A key synthon in the research and production of antiviral, anticancer, and other small-molecule drug candidates.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides, leveraging the biological activity of the pyrimidine core.
• Organic Synthesis Building Block: Employed in cross-coupling reactions, nucleophilic substitutions, and other transformations to introduce functionalized pyrimidine scaffolds.
• Material Science Research: Investigated as a precursor for specialty chemicals, ligands, or functional materials requiring halogenated heterocycles.
• Biochemical Research: Potential use as a tool compound or inhibitor in enzymatic and receptor binding studies.

Basic Information

Item	Detail
Product Name	6-Chloro-2-(trifluoromethyl)-4,5-pyrimidinediamine
CAS No.	709-57-9
Molecular Formula	C5H4ClF3N4
Molecular Weight	212.56 g/mol
Synonyms	4,5-Diamino-6-chloro-2-(trifluoromethyl)pyrimidine; 6-Chloro-2-trifluoromethylpyrimidine-4,5-diamine; 2-(Trifluoromethyl)-4,5-diamino-6-chloropyrimidine; 6-Chloro-2-(trifluoromethyl)-4,5-diaminopyrimidine; 4,5-Pyrimidinediamine, 6-chloro-2-(trifluoromethyl)-; 709-57-9; 6-Chloro-2-trifluoromethyl-4,5-pyrimidinediamine
EINECS	Contact for details

Quality Control

Our 6-Chloro-2-(trifluoromethyl)-4,5-pyrimidinediamine is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements of our global clientele. Certificates of Analysis (COA) documenting all critical parameters are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This compound is sensitive to fluoride and strong alkali; keep away from incompatible materials. Keep container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.