Description

L-2-Hydroxyphenylalanine is a non-proteinogenic aromatic amino acid derivative, serving as a key chiral building block and intermediate in advanced organic synthesis. Its unique phenolic side chain makes it valuable for the research and development of novel pharmaceuticals and bioactive compounds. This high-purity intermediate is essential for manufacturers and R&D laboratories in the pharmaceutical, agrochemical, and fine chemical sectors seeking to develop new therapeutic agents or complex molecules.

Application

• Pharmaceutical Intermediate: A critical chiral precursor in the synthesis of potential drug candidates, including enzyme inhibitors and receptor ligands.
• Biochemical Research: Used in studies of amino acid metabolism, enzyme mechanisms, and as a substrate analog in biochemical assays.
• Peptide Synthesis: Incorporated into custom peptides to introduce phenolic functionality for further modification or to study structure-activity relationships.
• Agrochemical Development: Serves as a building block for synthesizing novel herbicides, fungicides, or plant growth regulators.
• Fine Chemical Synthesis: Employed in the preparation of complex organic molecules, dyes, and specialty chemicals requiring a chiral phenolic amino acid motif.
• Reference Standard: Used as a high-purity analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	L-2-Hydroxyphenylalanine
CAS No.	709-16-0
Molecular Formula	C9H11NO3
Molecular Weight	181.19 g/mol
Synonyms	L-2-Hydroxyphenylalanine; (2S)-2-Amino-3-(2-hydroxyphenyl)propanoic acid; L-β-(2-Hydroxyphenyl)alanine; L-2-Hydroxy-phenylalanine; L-2-HPA; L-o-Tyrosine; 2-Hydroxy-L-phenylalanine; L-2-Hydroxybenzenealanine
EINECS	Contact for details

Quality Control

Our L-2-Hydroxyphenylalanine is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, detailing key parameters such as assay, chiral purity, and impurity profiles. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed to prevent absorption of atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee (L-Isomer)
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.