Description

5-Hydroxykynuramine is a significant endogenous metabolite in the tryptophan catabolic pathway, specifically the kynurenine pathway. This compound matters for its role as a biochemical precursor and potential neuromodulator, offering a key building block for advanced research and development. It is primarily needed by researchers and manufacturers in the pharmaceutical, life science, and biochemical synthesis sectors, particularly those focused on neurochemistry, metabolic studies, and the development of novel therapeutic agents.

Application

• Biochemical Research: Used as a critical reference standard and intermediate in studying the kynurenine pathway and its implications in neurological disorders.
• Pharmaceutical Development: Serves as a key precursor or active pharmaceutical ingredient (API) intermediate in the synthesis of novel neuroactive compounds.
• Metabolite Analysis: Essential for quantitative analysis in metabolomics studies, particularly in profiling tryptophan metabolism in biological samples.
• Enzymology Studies: Employed as a substrate to study the activity and kinetics of enzymes like monoamine oxidases (MAOs) and other related oxidases.
• Diagnostic Reagent Manufacturing: Utilized in the production of diagnostic kits and assays for detecting metabolic pathway dysregulation.
• Academic & Institutional Research: A vital tool for universities and research institutes investigating oxidative stress, aging, and immune response mechanisms.

Basic Information

Product Name	5-Hydroxykynuramine
CAS No.	708-23-6
Molecular Formula	C10H12N2O2
Molecular Weight	192.21 g/mol
Synonyms	5-Hydroxykynuramine; 5-HK; 2-Amino-4-(2-aminophenyl)-4-hydroxybutanoic acid (lactam form); 3-(2-Aminophenyl)-5-hydroxy-2,3-dihydro-1H-pyrrol-2-one; 5-Hydroxykynurenamine; Kynuramine, 5-hydroxy-
EINECS	Contact for details

Quality Control

Our 5-Hydroxykynuramine is produced under stringent quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept in a desiccated environment to prevent moisture absorption, which can compromise stability and purity. For long-term storage, consider inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.