Description

4,6-Dichloro-2-(Trifluoromethyl)Pyrimidine is a versatile halogenated pyrimidine building block of significant importance in advanced organic synthesis. Its molecular structure, featuring reactive chlorine atoms and a stable trifluoromethyl group, makes it a critical intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new active ingredients.

Application

This compound serves as a key synthetic intermediate in several high-value industrial and research applications:

• Pharmaceutical Intermediate: Core building block for the synthesis of novel drug candidates, including kinase inhibitors and antiviral agents.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, leveraging the bioactivity of the pyrimidine core.
• Material Science Research: Acts as a precursor for creating functionalized polymers and liquid crystals with specific electronic or optical properties.
• Organic Synthesis Reagent: Employed in cross-coupling reactions and nucleophilic substitutions to introduce the 2-(trifluoromethyl)pyrimidine moiety into complex molecules.
• Chemical Research & Development: A valuable scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.

Basic Information

Product Name	4,6-Dichloro-2-(Trifluoromethyl)Pyrimidine
CAS No.	705-24-8
Molecular Formula	C5HCl2F3N2
Molecular Weight	216.97 g/mol
Synonyms	2-(Trifluoromethyl)-4,6-dichloropyrimidine; 4,6-Dichloro-2-trifluoromethylpyrimidine; 4,6-Dichloro-2-(trifluoromethyl)-1,3-diazine; Pyrimidine, 4,6-dichloro-2-(trifluoromethyl)-; 4,6-Dichloro-2-(trifluoromethyl)pyrimidine; 2-Trifluoromethyl-4,6-dichloropyrimidine
EINECS	Contact for details

Quality Control

Our 4,6-Dichloro-2-(Trifluoromethyl)Pyrimidine is produced under stringent quality management systems. Every batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the exacting standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5% Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.