Description

2,3,5,6-Tetrafluoroaniline is a highly fluorinated aromatic amine derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the unique electronic and steric properties imparted by the tetrafluoro substitution pattern, which is essential for modifying material characteristics and biological activity. This compound is primarily needed by researchers and manufacturers in the pharmaceutical, agrochemical, and specialty materials industries for developing novel active ingredients and high-performance polymers.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of fluorinated drug candidates, particularly for central nervous system (CNS) agents and antimicrobials.
• Agrochemical Synthesis: Building block for creating advanced herbicides, fungicides, and pesticides with enhanced efficacy and environmental profile.
• Liquid Crystal & OLED Materials: Used in the development of fluorinated components for electronic display and lighting technologies.
• Polymer & Resin Modification: Imparts thermal stability, chemical resistance, and low surface energy to specialty polymers and coatings.
• Dye & Pigment Manufacturing: Intermediate for producing high-value, light-fast fluorinated dyes and pigments.
• Cross-coupling Reactions: Valuable substrate in Suzuki, Buchwald-Hartwig, and other palladium-catalyzed coupling reactions to create complex biaryl structures.

Basic Information

Product Name	2,3,5,6-Tetrafluoroaniline
CAS No.	700-17-4
Molecular Formula	C6H3F4N
Molecular Weight	165.09 g/mol
Synonyms	2,3,5,6-Tetrafluorobenzenamine; 2,3,5,6-Tetrafluoro-1-aminobenzene; 1-Amino-2,3,5,6-tetrafluorobenzene; Perfluoroaniline (ambiguous, but used); Benzenamine, 2,3,5,6-tetrafluoro-; TFA (context-specific); 2,3,5,6-Tetrafluorophenylamine
EINECS	211-843-5

Quality Control

Our 2,3,5,6-Tetrafluoroaniline is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment to support your R&D and production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	88 - 92 °C
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.