Description

5,5-Diethyl-2-Thiobarbituric Acid CAS NO 77-32-7 is a specialized thiobarbituric acid derivative, a key heterocyclic compound in organic synthesis and pharmaceutical research. This high-purity intermediate is valued for its role in the development of novel therapeutic agents and as a versatile building block in medicinal chemistry. It is primarily utilized by research institutions and pharmaceutical manufacturers focused on central nervous system (CNS) drug discovery, analytical chemistry, and the synthesis of complex organic molecules.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of barbiturate analogs and other potential CNS-active compounds.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and the development of new chemical entities.
• Analytical Chemistry: Used as a reagent or standard in chromatographic analysis and method development for related compounds.
• Biochemical Research: Employed in studies investigating enzyme interactions or as a model compound in metabolic pathway research.
• Organic Synthesis: Acts as a building block for the construction of more complex heterocyclic systems and specialty chemicals.

Basic Information

Product Name	5,5-Diethyl-2-Thiobarbituric Acid
CAS No.	77-32-7
Molecular Formula	C8H12N2O2S
Molecular Weight	200.26 g/mol
Synonyms	5,5-Diethyl-2-thioxodihydropyrimidine-4,6(1H,5H)-dione; 5,5-Diethyl-2-thiobarbituric acid; 2-Thio-5,5-diethylbarbituric acid; NSC 401565; 5,5-Diethyl-2-mercaptobarbituric acid; Thiobarbituric acid, 5,5-diethyl-; 5,5-Diethyl-2-sulfanylidene-1,3-diazinane-4,6-dione
EINECS	201-016-8

Quality Control

Our 5,5-Diethyl-2-Thiobarbituric Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and development applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed to minimize exposure to atmospheric moisture and light to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.