Description

2,2,2-Tribromoethanol CAS NO 75-80-9 is a halogenated tertiary alcohol primarily recognized for its potent anesthetic and sedative properties in laboratory animal research. Its value lies in providing a reliable and controlled method for inducing prolonged anesthesia in small mammals, particularly mice and rats, for surgical and experimental procedures. This compound is essential for research institutions, pharmaceutical development labs, and contract research organizations (CROs) requiring consistent and reproducible animal models.

Application

• Laboratory Animal Anesthesia: Primary use for inducing and maintaining surgical-plane anesthesia in rodents (mice, rats) for biomedical research.
• Veterinary Research: Used in experimental veterinary medicine for sedation and anesthesia protocols in small animal studies.
• Pharmaceutical Safety Testing: Employed to anesthetize animals during prolonged toxicology and efficacy studies for new drug candidates.
• Physiological Studies: Facilitates stable anesthesia for invasive procedures like catheterization, imaging, and electrophysiological recordings.
• Surgical Model Preparation: Critical for creating consistent animal models of disease or injury that require anesthetic recovery.
• Compound for Chemical Synthesis: Serves as a specialized brominating agent or building block in organic synthesis for pharmaceutical intermediates.

Basic Information

Product Name	2,2,2-Tribromoethanol
CAS No.	75-80-9
Molecular Formula	C2H3Br3O
Molecular Weight	282.76 g/mol
Synonyms	Tribromoethanol; Avertin (with amylene hydrate); Ethanol, 2,2,2-tribromo-; 2,2,2-Tribromoethyl alcohol; NSC 66488; Tribromoethyl alcohol; Tertiary tribromoethanol
EINECS	200-908-7

Quality Control

Our 2,2,2-Tribromoethanol is produced and tested to meet the stringent requirements of research and pharmaceutical applications. We provide material that conforms to high-purity standards, with comprehensive testing for identity, potency, and impurity profiles. Certificates of Analysis (COA) detailing batch-specific results for assay, related substances, and residual solvents are available upon request to ensure full traceability and compliance with your internal quality protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is light-sensitive (store away from light) and easily oxidized (store under inert atmosphere). For long-term stability, consider storage under an inert gas such as nitrogen or argon. Keep container tightly sealed when not in use to minimize exposure to air and moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or lumps
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Melting Point	79°C - 82°C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.