Description

Papaveretum-Hyoscine is a specialized pharmaceutical preparation combining the analgesic and sedative properties of papaveretum with the anticholinergic effects of hyoscine (scopolamine). This compound is primarily utilized in pre-anesthetic medication and for the management of severe pain, particularly in palliative and post-operative care settings. It is a critical material for pharmaceutical manufacturers and compounding pharmacies developing controlled-release formulations for clinical use. The product is supplied under stringent quality control to ensure batch-to-batch consistency and therapeutic efficacy.

Application

• Pre-anesthetic Medication: Used to induce sedation, reduce anxiety, and decrease respiratory secretions prior to surgical procedures.
• Palliative Care Formulations: A key active ingredient in medications designed for the management of severe, intractable pain in terminal illness.
• Post-operative Analgesia: Incorporated into specialized delivery systems for controlled pain relief following major surgery.
• Antispasmodic and Anti-emetic Therapy: Leverages the hyoscine component to relieve smooth muscle spasms and nausea.
• Pharmaceutical R&D: Serves as a reference standard and raw material for the development of new analgesic and sedative drug combinations.
• Hospital Compounding: Used by hospital pharmacies for preparing patient-specific doses where commercial formulations are unsuitable.

Basic Information

Product Name	Papaveretum-Hyoscine
CAS No.	127060-78-0
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Papaveretum and Scopolamine; Omnopon-Scopolamine; Narcopon-Scopolamine; Opium Alkaloids Hydrochlorides with Hyoscine Hydrobromide; Pre-anesthetic Opioid-Anticholinergic Combination; Scopolamine and Papaveretum; Hyoscine Papaveretum
EINECS	Contact for details

Quality Control

Our Papaveretum-Hyoscine is manufactured and tested to meet exacting standards suitable for pharmaceutical application. Each batch is subjected to rigorous identity, purity, and potency testing, including assay for individual alkaloid components and related substance analysis. We adhere to cGMP (current Good Manufacturing Practice) guidelines, and a comprehensive Certificate of Analysis (COA) documenting all test results is provided with every shipment to ensure full traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a low-humidity environment to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (Total Alkaloids)	98.0% - 102.0%
Assay (Hyoscine Hydrobromide)	As per label claim ±5%
Related Substances (HPLC)	NMT 2.0% total impurities
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	NMT 2.0%
Heavy Metals	NMT 20 ppm
Microbiological Enumeration	Complies with Ph. Eur. 2.6.12/2.6.13

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.