Description

Methohexital is a short-acting barbiturate derivative widely recognized for its potent anesthetic and sedative properties. Its primary value lies in providing rapid induction and recovery, making it a critical agent for controlled procedural sedation. This compound is essential for pharmaceutical manufacturers and research institutions developing injectable anesthetics and studying central nervous system (CNS) depressants. Methohexital CAS NO 18652-93-2 is supplied under strict quality control to ensure reliability for sensitive applications.

Application

• Injectable Anesthetic Formulations: As the active pharmaceutical ingredient (API) in short-duration general anesthesia.
• Procedural Sedation: For medical procedures requiring brief, deep sedation, such as electroconvulsive therapy (ECT).
• Veterinary Medicine: Used in veterinary practice for the induction of anesthesia in animals.
• Pharmacological Research: A reference standard in studies investigating barbiturate pharmacology, GABA receptor modulation, and sedative-hypnotic mechanisms.
• Analytical Standard: Serves as a high-purity standard for quality control testing in pharmaceutical laboratories.
• Chemical Synthesis: An intermediate for the research and development of novel barbiturate analogs or related CNS-active compounds.

Basic Information

Product Name	Methohexital
CAS No.	18652-93-2
Molecular Formula	C14H18N2O3
Molecular Weight	262.30 g/mol
Synonyms	Methohexitone; 1-Methyl-5-(1-methyl-2-pentyn-1-yl)-5-(2-propen-1-yl)-2,4,6(1H,3H,5H)-pyrimidinetrione; Brevital; Brietal; Methohexital Sodium (salt form); Methylhexobital; Enallynymal; A-1770
EINECS	242-463-9

Quality Control

Our Methohexital is manufactured and tested to meet high-purity standards suitable for pharmaceutical research and development. Each batch undergoes rigorous analytical testing, including identity confirmation, purity assay, and impurity profiling. A comprehensive Certificate of Analysis (COA) is provided, detailing results against established specifications to ensure batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.