Description

S-(+)-Isoflurane is the single enantiomer form of the widely used inhalation anesthetic, isoflurane. This optically pure compound is of significant interest for advanced pharmacological research, particularly in studying stereoselective effects and receptor interactions. It is primarily utilized by pharmaceutical R&D laboratories, academic institutions, and manufacturers developing next-generation anesthetic agents or conducting detailed neuropharmacological studies.

Application

• Pharmacological Research: Used as a reference standard and active agent in studies investigating the stereospecific mechanisms of volatile anesthetics.
• Neuroscience Studies: Employed in experimental models to examine the effects of specific enantiomers on neuronal receptors and synaptic transmission.
• Analytical Method Development: Serves as a high-purity standard for developing and validating chiral analytical methods, such as chiral gas chromatography (GC) or HPLC.
• Preclinical Evaluation: Utilized in animal studies to assess the potency, efficacy, and safety profile of the (S)-enantiomer compared to the racemic mixture or the (R)-enantiomer.
• Chemical Synthesis: Acts as a chiral building block or intermediate in the synthesis of more complex, stereochemically defined molecules for medicinal chemistry.

Basic Information

Product Name	S-(+)-Isoflurane
CAS No.	133098-05-2
Molecular Formula	C3H2ClF5O
Molecular Weight	184.49 g/mol
Synonyms	(S)-Isoflurane; (+)-Isoflurane; (S)-(+)-1-Chloro-2,2,2-trifluoroethyl difluoromethyl ether; (S)-1-Chloro-2,2,2-trifluoroethyl difluoromethyl ether; Forane (S-enantiomer); Aerrane (S-enantiomer); (S)-2-Chloro-2-(difluoromethoxy)-1,1,1-trifluoroethane; Isoflurane S-(+) enantiomer
EINECS	Contact for details

Quality Control

Our S-(+)-Isoflurane is produced and handled under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assay, enantiomeric excess (ee) determination, and identification of organic and inorganic impurities. A Certificate of Analysis (COA) detailing the results for purity, identity, and specific tests is provided with every shipment to ensure traceability and compliance with your research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area. Due to its highly volatile nature, ensure containers are kept upright and sealed when not in use. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Clear, colorless liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 99.0%
Enantiomeric Excess (Chiral GC)	≥ 99.5% ee
Related Substances (GC)	≤ 0.5% total
Water Content (KF)	≤ 0.1%
Residue on Evaporation	≤ 0.01%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.