Description

Eltanolone is a synthetic neuroactive steroid with significant anesthetic and sedative properties. Its primary value lies in its potent and rapid-acting effects on the central nervous system, making it a compound of high interest for advanced pharmaceutical research and development. This product is essential for researchers and manufacturers in the pharmaceutical industry, particularly those focused on developing novel anesthetic agents, neurosteroid-based therapies, and studying GABAA receptor modulation. Eltanolone CAS NO 128-20-1 is supplied as a high-purity material to support these critical applications.

Application

• Pharmaceutical Intermediate: Serves as a key starting material or intermediate in the synthesis of advanced neuroactive steroid drugs.
• Anesthetic Research: Used in preclinical and clinical research for developing new intravenous anesthetic agents due to its favorable recovery profile.
• Neurosteroid Studies: A vital reference standard and active compound in neuroscience research investigating GABAergic neurotransmission and neurosteroid pharmacology.
• Sedative-Hypnotic Development: Employed in R&D for creating novel sedative or hypnotic medications with potential applications in intensive care and procedural sedation.
• Reference Standard: Used as a high-purity analytical standard in quality control laboratories for method development and validation.
• Biochemical Research: Applied in studies exploring the structure-activity relationships (SAR) of steroid interactions with neuronal receptors.

Basic Information

Product Name	Eltanolone
CAS No.	128-20-1
Molecular Formula	C21H34O2
Molecular Weight	318.50 g/mol
Synonyms	Pregnanolone; 3α-Hydroxy-5β-pregnan-20-one; 5β-Pregnan-3α-ol-20-one; (3α,5β)-3-Hydroxypregnan-20-one; Eltanolone; LTR-0120; Minaxolone (related compound); Presuren; Alphaxalone (isomer)
EINECS	204-879-7

Quality Control

Our Eltanolone is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and pharmaceutical applications. Each batch is subjected to comprehensive analytical testing, including identity confirmation by spectroscopic methods and purity assessment by chromatographic techniques. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting the specific results for all tested parameters to ensure compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed when not in use to protect the contents from moisture and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.