Description

Methohexital CAS NO 151-83-7 is a short-acting barbiturate derivative belonging to the class of ultra-short-acting anesthetic agents. It is valued for its rapid onset and short duration of action, making it a critical agent for controlled induction of anesthesia. This compound is primarily required by the pharmaceutical industry for the formulation of injectable anesthetic solutions used in surgical and diagnostic procedures.

Application

• Intravenous Anesthetic Agent: Primary use for the induction of general anesthesia prior to surgery.
• Procedural Sedation: Used in short medical and dental procedures requiring deep sedation.
• Electroconvulsive Therapy (ECT): Employed as an anesthetic to modify seizure activity and provide muscle relaxation.
• Veterinary Anesthesia: Utilized for the induction of anesthesia in various animal species.
• Pharmaceutical Intermediate: Serves as a key starting material or intermediate in the synthesis of other specialized barbiturate compounds.
• Research & Development: Used in preclinical and clinical studies investigating anesthetic mechanisms, pharmacokinetics, and central nervous system depressants.

Basic Information

Product Name	Methohexital
CAS No.	151-83-7
Molecular Formula	C14H18N2O3
Molecular Weight	262.30 g/mol
Synonyms	Methohexitone; 1-Methyl-5-(1-methyl-2-pentyn-1-yl)-5-(2-propen-1-yl)-2,4,6(1H,3H,5H)-pyrimidinetrione; Brevital; Brietal; Enallynymalum; Methohexital Sodium; Methylhexabital; Methylhexobital; NSC-69871
EINECS	205-796-5

Quality Control

Our Methohexital is manufactured under strict quality systems to ensure it meets the high standards required for pharmaceutical applications. Each batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling via techniques such as HPLC and IR spectroscopy. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.