Description

3,3'-Diiodothyronine is a key iodinated thyronine derivative, serving as a crucial intermediate in thyroid hormone metabolism and research. This compound is of significant interest for its role in studying the structure-activity relationships of thyroid hormones and their analogs. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and manufacturers of biochemical reagents focused on endocrinology and metabolic studies.

Application

• Pharmaceutical Research & Development: As a critical reference standard and intermediate in the synthesis and study of thyroid hormone analogs and potential therapeutics.
• Biochemical Research: Used in enzymatic studies to investigate the deiodination pathways and metabolic fate of thyroid hormones.
• Endocrinology Studies: Employed as a tool compound in in vitro and in vivo models to understand thyroid hormone action and receptor binding.
• Diagnostic Reagent Manufacturing: Serves as a raw material or calibrant in the production of immunoassays and diagnostic kits for thyroid function testing.
• Academic Research: A valuable compound for university laboratories conducting fundamental research on hormone biochemistry and signal transduction.

Basic Information

Product Name	3,3'-Diiodothyronine
CAS No.	70-40-6
Molecular Formula	C15H13I2NO4
Molecular Weight	525.08 g/mol
Synonyms	3,3'-T2; 3,3'-Diiodo-L-thyronine; O-(4-Hydroxy-3-iodophenyl)-3-iodo-L-tyrosine; 3,3'-Diiodothyronine; T2; DIT2; 3,3'-Diiodo-thyronine; L-3,3'-Diiodothyronine
EINECS	200-734-5

Quality Control

Our 3,3'-Diiodothyronine is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation (IR, MS). We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with research and development grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.