Description

1-[(6-Methyl-2,4-Dioxo-1,2,3,4-Tetrahydropyrimidin-5-Yl)Sulfonyl]Piperidine-3-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its unique sulfonyl-linked heterocyclic structure. This compound is of significant value in medicinal chemistry for the development of novel therapeutic agents, particularly as a key building block in protease inhibitor research. It is primarily needed by R&D scientists and process chemists in the pharmaceutical and biotechnology industries engaged in synthesizing new chemical entities for antiviral and other targeted therapies.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of active pharmaceutical ingredients (APIs), especially for protease inhibitors.
• Medicinal Chemistry Research: Used as a sophisticated scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Bioconjugation & Probe Development: The carboxylic acid functional group allows for conjugation to other molecules, useful in creating chemical probes for biological target identification.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and scale-up of novel compounds for clinical trials.
• Academic Research: Utilized in university and institutional labs for fundamental studies in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	1-[(6-Methyl-2,4-Dioxo-1,2,3,4-Tetrahydropyrimidin-5-Yl)Sulfonyl]Piperidine-3-Carboxylic Acid
CAS No.	697258-18-7
Molecular Formula	C12H15N3O6S
Molecular Weight	329.33 g/mol
Synonyms	5-[(3-Carboxypiperidin-1-yl)sulfonyl]-6-methylpyrimidine-2,4(1H,3H)-dione; 1-[(6-Methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)sulfonyl]piperidine-3-carboxylic acid; 5-(3-Carboxypiperidine-1-sulfonyl)-6-methyluracil; 6-Methyl-5-(3-carboxypiperidine-1-sulfonyl)uracil; Piperidine-3-carboxylic acid, 1-[(6-methyl-2,4-dioxo-1,2,3,4-tetrahydro-5-pyrimidinyl)sulfonyl]-
EINECS	Contact for details

Quality Control

Our 1-[(6-Methyl-2,4-Dioxo-1,2,3,4-Tetrahydropyrimidin-5-Yl)Sulfonyl]Piperidine-3-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.