Description

Fmoc-Mebph-Oh CAS NO 696615-48-2 is a high-purity, protected amino acid derivative essential for advanced peptide synthesis. This compound serves as a critical building block in solid-phase peptide synthesis (SPPS), enabling the precise construction of complex peptide sequences. It is primarily utilized by pharmaceutical researchers, biotech companies, and CROs engaged in the development of novel therapeutic peptides, peptidomimetics, and biochemical probes.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key intermediate for the controlled, sequential addition of amino acids in automated peptide synthesizers.
• Pharmaceutical Research & Development: Used in the discovery and development of peptide-based drug candidates for various therapeutic areas.
• Peptidomimetic Design: Incorporates non-natural amino acid structures to enhance the metabolic stability and bioavailability of peptide leads.
• Bioconjugation and Probe Synthesis: Facilitates the site-specific labeling of peptides with fluorophores, biotin, or other functional tags for diagnostic and research applications.
• Combinatorial Chemistry Libraries: Employed to generate diverse libraries of peptide analogs for high-throughput screening against biological targets.
• Academic Research: Supports fundamental studies in biochemistry, medicinal chemistry, and chemical biology involving peptide structure and function.

Basic Information

Product Name	Fmoc-Mebph-Oh
CAS No.	696615-48-2
Molecular Formula	C26H25NO5
Molecular Weight	431.48 g/mol
Synonyms	Fmoc-4-(Methylsulfonyl)-L-phenylalanine; Fmoc-(4-MeSO2)-Phe-OH; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-4-(methylsulfonyl)-L-phenylalanine; (2S)-2-[(9H-Fluoren-9-ylmethoxy)carbonylamino]-3-[4-(methylsulfonyl)phenyl]propanoic acid; Fmoc-Phe(4-SO2Me)-OH; Fmoc-L-Phe(4-SO2CH3)-OH; Fmoc-4-Methylsulfonyl-L-phenylalanine
EINECS	Contact for details

Quality Control

Our Fmoc-Mebph-Oh is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, typically ≥98% (by HPLC). Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards for fine chemical and pharmaceutical intermediate production, ensuring material integrity for critical research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.