Description

3-Quinolinecarboxylic Acid, 1-Cyclopropyl-7-[4-[[(2,4-Dichlorobenzoyl)Amino]Thioxomethyl]-1-Piperazinyl]-6-Fluoro-1,4-Dihydro-4-Oxo- is a high-purity, complex heterocyclic compound that serves as a critical advanced pharmaceutical intermediate. Its value lies in its sophisticated molecular architecture, which is essential for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in the fluoroquinolone antibiotic class. This compound is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development and production of next-generation antibacterial agents and other specialized fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel fluoroquinolone antibiotics and other therapeutic agents.
• Antibacterial Drug Research: Used in R&D for developing new compounds targeting resistant bacterial strains.
• Organic Synthesis: Serves as a versatile precursor for constructing complex heterocyclic systems in medicinal chemistry.
• Chemical Reference Standard: Employed as a high-purity standard for analytical method development and quality control in API manufacturing.
• Biochemical Research: Utilized in studies investigating enzyme inhibition and molecular binding mechanisms.

Basic Information

Item	Details
Product Name	3-Quinolinecarboxylic Acid, 1-Cyclopropyl-7-[4-[[(2,4-Dichlorobenzoyl)Amino]Thioxomethyl]-1-Piperazinyl]-6-Fluoro-1,4-Dihydro-4-Oxo-
CAS No.	696604-35-0
Molecular Formula	C23H19Cl2FN4O3S
Molecular Weight	521.39 g/mol
Synonyms	1-Cyclopropyl-7-[4-[[(2,4-dichlorobenzoyl)amino]thioxomethyl]-1-piperazinyl]-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid; 1-Cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(4-((2,4-dichlorobenzoyl)carbamothioyl)piperazin-1-yl)quinoline-3-carboxylic acid; 696604-35-0; Gatifloxacin intermediate; Gatifloxacin derivative; Fluoroquinolone intermediate; Advanced pharmaceutical intermediate (API intermediate)
EINECS	Contact for details

Quality Control

Our 3-Quinolinecarboxylic Acid derivative is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring the material meets the stringent requirements for pharmaceutical R&D and manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere if necessary to prevent degradation and ensure long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.