Description

5-Chloro-2,4-Difluorobenzaldehyde is a versatile and high-purity fluorinated aromatic aldehyde building block. This compound is critical for the synthesis of complex molecules, particularly in the pharmaceutical and agrochemical sectors, where its difluoro and chloro substituents enable precise modulation of biological activity and physicochemical properties. It is an essential intermediate for researchers and manufacturers developing active pharmaceutical ingredients (APIs), advanced crop protection agents, and specialty materials.

Application

• Pharmaceutical Intermediate: A key synthon for the preparation of drug candidates, especially in kinase inhibitor and anti-inflammatory research.
• Agrochemical Synthesis: Used in the manufacture of advanced herbicides and fungicides, leveraging its halogenated structure for enhanced efficacy.
• Liquid Crystal & OLED Materials: Serves as a precursor in the synthesis of fluorinated organic electronic materials.
• Cross-Coupling Reactions: The aldehyde and halogen groups make it a valuable substrate for Suzuki, Sonogashira, and other palladium-catalyzed couplings.
• Organic Synthesis Building Block: Employed in the synthesis of heterocycles, Schiff bases, and other complex organic frameworks.
• Chemical Research & Development: Used in academic and industrial R&D for exploring new synthetic methodologies and material properties.

Basic Information

Product Name	5-Chloro-2,4-Difluorobenzaldehyde
CAS No.	695187-29-2
Molecular Formula	C7H3ClF2O
Molecular Weight	176.55 g/mol
Synonyms	2,4-Difluoro-5-chlorobenzaldehyde; 5-Chloro-2,4-difluorobenzenecarboxaldehyde; Benzaldehyde, 5-chloro-2,4-difluoro-; 695187-29-2; 5-Chloro-2,4-difluoro benzaldehyde
EINECS	Contact for details

Quality Control

Our 5-Chloro-2,4-Difluorobenzaldehyde is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications. Our quality commitment ensures the material meets the stringent requirements for pharmaceutical and advanced chemical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store under an inert atmosphere (e.g., nitrogen) for long-term preservation. Keep away from strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.